PathologybioRxivPreprint
Pro-renin Receptor Inhibited ABCA1/G1 Expression Associated with Low HDL-c and Promoted Atherosclerosis
Yubing Dong, Wei Zhang, Wanyu Liu…·Wei Song
This study shows that prorenin binding to (P)RR inhibits ABCA1/ABCG1 expression and cholesterol efflux, leading to dyslipidemia and atherosclerosis in hypertension.
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