Cancer BiologyCancer ResearchPeer-reviewed
Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
Joan Jacob, Yasuaki Anami, Peyton C. High…·Kendra S. Carmon
This study develops and tests EREG-targeting ADCs showing efficacy in both RAS mutant and wildtype CRC, with high potency and safety in preclinical models.