Qi Guo

This study shows that DAP12 deficiency reduces tau-induced inflammation and myelin loss in mice, despite increased tau pathology, by altering microglia-oligodendrocyte interactions.

The paper investigates cell-to-cell communication in Alzheimer's disease to characterize disease biology and suggest new avenues for therapeutic intervention.

scBSP identifies spatially variable genes from spatial transcriptomic data efficiently and accurately across different sequencing techniques and resolutions.

This study uses spatial transcriptomics to identify gene signatures in the human temporal cortex linked to Alzheimer's pathology.