Author

Simone Ciofi‐Baffoni

University of FlorenceORCID 0000-0002-2376-3321Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alessia LaiiD· 1 shared Andrea TrabocchiiD· 1 shared Annalisa BergnaiD· 1 shared Arianna GabrieliiD· 1 shared Carla Della VenturaiD· 1 shared Denise PoireiD· 1 shared Elena LenciiD· 1 shared Hannah Florance· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Alessia LaiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 17, 2026

An intrinsically disordered region controls viperin (SAND) antiviral synthesis via a clamp-and-latch mechanism

Mengdi Wu, Denise Poire, Hannah Florance…·Kourosh Honarmand Ebrahimi

This study identifies an intrinsically disordered region (IDR) in viperin that enables rNTP selection via a clamp-and-latch mechanism, revealing a new aspect of antiviral enzyme function.

DOI 10.64898/2026.09.10.750538

humanrat

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MicrobiologybioRxivPreprintOct 30, 2025

In vitro Characterization of Peptidomimetic Proteolysis Targeting Chimera (PROTAC) as a Degrader of 3-Chymotrypsin-Like Protease (Mpro/3CLpro) against SARS-CoV-2

Mirko Giuseppe Liturri, Annalisa Bergna, Alessia Lai…·Stefano Rusconi

The paper characterizes FT235, a PROTAC degrader of SARS-CoV-2 3CLpro, showing antiviral activity and reduced cytotoxicity.

DOI 10.1101/2025.10.30.685646

experimental assaydrug response / drug discovery

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