BAF chromatin complexes do not mediate GLI transcriptional repression of Hedgehog target genes
Janani Ramachandran, Wanlu Chen, Rachel K. Lex, Kathryn E. Windsor, Hyunji Lee, Tingchang Wang, Weiqiang Zhou, Hongkai Ji, Steven A. Vokes
The paper shows SMARCC1 does not mediate GLI3 repression of Hedgehog target genes, as it maintains chromatin accessibility at GLI-regulated enhancers independently of GLI3.
Developmental Biology · Oct 5, 2023Peer-reviewedDevelopmental Biology