Author

James Denholm

AstraZeneca (United Kingdom)ORCID 0000-0002-2389-3134Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:batch correction / integration· 1 Research Focus:database / resource· 1 Assay:imaging· 1 Assay:metabolomics· 1 Organism:mouse· 1 Research Focus:software / tool· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Aleksandr ZakiroviD· 1 shared Anna Ollerstam· 1 shared Azam HamidinekooiD· 1 shared Eleanor C WilliamsiD· 1 shared Gregory R. HammiD· 1 shared Irina MohorianuiD· 1 shared Javier Escudero MorlanesiD· 1 shared Jennifer Y. TaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Aleksandr ZakirovORCID

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1 paper

Recent·Most cited

Spatially resolved integrative analysis of transcriptomic and metabolomic changes in tissue injury studies

Eleanor C Williams, Lovisa Franzén, Martina Olsson Lindvall, Gregory R. Hamm, Steven Oag, Muntasir Mamun Majumder, James Denholm, Azam Hamidinekoo, Javier Escudero Morlanes, Marco Vicari, Joakim Lundeberg, Laura C. Setyo, Trevor M. Godfrey, Lívia S. Eberlin, Aleksandr Zakirov, , Irina Mohorianu

The paper introduces MAGPIE, a framework for integrating spatial transcriptomics, metabolomics, and tissue morphology data, demonstrating its application in studying drug-induced pulmonary fibrosis.

Nature Communications · Jan 7, 2026Peer-reviewedBioinformatics