ImmunologybioRxivPreprint
The buried S2 apex of SARS-CoV-2 spike elicits an immunodominant germline-restricted public antibody response
Suncheol Park, Jacob Mischka, Nisreen M.A. Okba…·Andrew B. Ward
This study identifies an immunodominant S2 apex epitope in SARS-CoV-2 that elicits a public antibody clonotype, highlighting its role as a barrier to universal coronavirus vaccines.
DOI 10.64898/2026.02.18.706653