WSB1 Regulates c-Myc Expression Through β-catenin Signaling and Forms a Feedforward Circuit Promoting the Development of Cancer.
Xiaomeng Gao, Yanling Gong, Jieqiong You, Yuan Guang Meng, Haiying Zhu, Liang Fang, Hong Zhu, Meidan Ying, Qiaojun He, Bo Yang, Ji Cao
This study identifies a feedforward circuit between WSB1 and c-Myc that promotes cancer development through β-catenin signaling, suggesting a potential therapeutic target.
bioRxiv · Sep 25, 2020 · PreprintMolecular Biology