Author

Mohan Maruthi Sena

Department of Molecular Oncology, Cancer Institute (WIA), Chennai, IndiaORCID 0000-0002-2398-700XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:metagenomics· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Aayushi GuptaiD· 1 shared Ananya GanapathyiD· 1 shared Bipin SinghiD· 1 shared Mayilvahanan BoseiD· 1 shared Narayanan MadaboosiiD· 1 shared Ramakrishnan Ayloor SeshadriiD· 1 shared Viveak KumariD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 11 mutual co-author links

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1 shared paperPharmacology & Toxicology

Aayushi GuptaORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintNov 2, 2026

Target Specific Conformational Flexibility and Electrostatic Complementarity Modulate LTNF10 Peptide Binding to Phospholipase A2 Variants from Snake Venoms

Aayushi Gupta, Mohan Maruthi Sena, Bipin Singh

This study investigates how charge and conformational changes in a peptide affect its binding to different snake venom PLA2 variants, revealing structural and electrostatic factors influencing affinity.

DOI 10.64898/2026.10.30.761852

protein structureprotein sequence

Cancer BiologybioRxivPreprintSep 23, 2025

Integrative Microbiome Profiling of Colorectal Cancer Across South Asian and Western Cohorts Using Interpretable Machine Learning

Mohan Maruthi Sena, Ananya Ganapathy, Viveak Kumar…·Mayilvahanan Bose

This study uses machine learning to identify microbial biomarkers for early colorectal cancer detection across South Asian and Western cohorts, finding distinct microbial signatures associated with CRC.

DOI 10.1101/2025.09.23.677677

humanmetagenomics