Author

Santiago Costantino

Hôpital Maisonneuve-RosemontORCID 0000-0002-2454-2635Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

Alireza TavakolpournegariiD· 1 shared Clément PlayoutiD· 1 shared Daniel G. CyriD· 1 shared Hugo WürteleiD· 1 shared Julie DufresneiD· 1 shared Marie Carole BoucheriD· 1 shared Mary GregoryiD· 1 shared Nicolas Desjardins‐LecavalieriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alireza TavakolpournegariORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedApr 1, 2026

DNAi: an open-source AI tool for unbiased DNA fiber analysis

Clément Playout, Yosra Mehrjoo, Renaud Duval…·Hugo Würtele

DNAi is an open-source deep learning tool that automates DNA fiber analysis, matching human performance in segmentation and length measurement.

2 citations

deep learningbenchmarking

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Pharmacology & ToxicologybioRxivPreprintMar 26, 2026

Polystyrene Nanoplastics Accumulate in Murine Cortex and Induce Transient Microglial Activation via Endolysosomal Retention

Alireza Tavakolpournegari, Unikrishnan Kannan, Mary Gregory…·Daniel G. Cyr

DOI 10.64898/2026.03.24.712727

mousebulk RNA-seq

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BiophysicsBiophysical JournalPeer-reviewedNov 14, 2025

A new approach for high-content traction force microscopy to characterize large cell ensembles

Nicolas Desjardins‐Lecavalier, Santiago Costantino

This paper introduces a new method using the Demons algorithm for high-content traction force microscopy to analyze large cell ensembles and improve force measurement accuracy and efficiency.

1 citation

imagingdeep learning

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