Ryosuke Yamamoto

This study maps the spatiotemporal cellular landscape of the human fetal utricle using single-nucleus transcriptomics and spatial transcriptomics, revealing cell states and regulatory pathways involved in vestibular development.

The paper develops an in vitro model of neonatal and adult stria vascularis and uses single-cell RNA sequencing to identify key genes and pathways involved in SV proliferation and maintenance.

This study shows that EBF1 is crucial for inner ear development, regulating cochlear structure and cell numbers, and is necessary for normal hearing function.

The paper uses single-cell RNA sequencing to study fate conversion of supporting cells to hair cells in chick auditory epithelium, identifying a stepwise process involving precursor states and TGFβ signaling.