Alain Dabdoub

A comparative single-cell transcriptomic atlas for diverse populations of vertebrate hair cells

The paper constructs a cross-species single-cell transcriptomic atlas of hair cells across multiple vertebrates and identifies conserved and species-specific gene expression programs.

Spatiotemporal cellular landscape of the human utricle sensory epithelium

This study maps the spatiotemporal cellular landscape of the human fetal utricle using single-nucleus transcriptomics and spatial transcriptomics, revealing cell states and regulatory pathways involved in vestibular development.

Trophic and temporal dynamics of macrophage biology in human inner ear organogenesis

The paper identifies seven macrophage subtypes in the human inner ear across development and adulthood using scRNA-seq data, linking them to specific developmental stages and gene expression profiles.

Molecular differences between neonatal and adult stria vascularis from organotypic explants and transcriptomics

The paper develops an in vitro model of neonatal and adult stria vascularis and uses single-cell RNA sequencing to identify key genes and pathways involved in SV proliferation and maintenance.

Pericytes control vascular stability and auditory spiral ganglion neuron survival

This study shows pericytes support vascular stability and spiral ganglion neuron survival through exosome-mediated VEGF-A signaling, impacting hearing.