Human placental trophoblasts support sustained Treponema pallidum replication and reveal new candidate host pathways implicated in congenital syphilis
Eliza McColl, Diane G. Edmondson, Bridget D. DeLay, Karan Gautam Kaval, Steven J. Bark, Steven J. Norris, Indira U. Mysorekar
This study shows human placental trophoblasts support long-term Treponema pallidum replication and identifies host pathways involved in congenital syphilis.
bioRxiv · May 10, 2026 · PreprintMicrobiology