Alberto Darszon

Fluid flow reconstruction around a free-swimming sperm in 3D

This study reconstructs fluid flow around a free-swimming human sperm using 3D microscopy and numerical models, revealing counter-rotating vortices in the flow pattern.

Nanoscopic resolution within a single imaging frame

The paper introduces MSSR, a super resolution method that improves spatial resolution beyond the diffraction limit and outperforms existing approaches in denoising.

Discrete dynamic model of the mammalian sperm acrosome reaction: the influence of acrosomal pH and biochemical heterogeneity

The paper presents a discrete mathematical model of the human sperm acrosome reaction that shows acrosomal pH and biochemical heterogeneity regulate the reaction.

Mathematical model reveals that heterogeneity in the number of ion transporters regulates the fraction of mouse sperm capacitation

The paper develops a mathematical model to show that variability in ion transporter numbers among mouse sperm regulates the fraction that undergo capacitation.

Modular mathematical analysis of the control of flagellar Ca2+-spike trains produced by CatSper and CaV channels in sea urchin sperm

The paper uses a mathematical model to determine which channels control calcium spikes in sea urchin sperm, concluding that CatSper channels are responsible.