Jorge Carneiro

Discrete dynamic model of the mammalian sperm acrosome reaction: the influence of acrosomal pH and biochemical heterogeneity

The paper presents a discrete mathematical model of the human sperm acrosome reaction that shows acrosomal pH and biochemical heterogeneity regulate the reaction.

Partitioning stable and unstable expression level variation in cell populations: a theoretical framework with application to the T cell receptor

The paper develops a framework to distinguish stable and unstable expression variation in cell populations and applies it to TCR expression in CD4 T cells, finding 70% stable variance in polyclonal populations and over 80% volatile variance in isogenic populations.

Modular mathematical analysis of the control of flagellar Ca2+-spike trains produced by CatSper and CaV channels in sea urchin sperm

The paper uses a mathematical model to determine which channels control calcium spikes in sea urchin sperm, concluding that CatSper channels are responsible.