NeurosciencebioRxivPreprint
Notch inhibition rescues TNF-α mediated block in multiciliated ependymal cell differentiation: Implications for hydrocephalus therapy
Clementine Adeyemi, Khadar M. Abdi
This study shows that TNF-α inhibits multiciliated ependymal cell differentiation by upregulating Notch pathway effectors, and that Notch inhibition rescues this process, suggesting a potential therapeutic target for hydrocephalus.
DOI 10.1101/2022.11.25.517974