Francisco M. Martín-Zamora

The paper identifies a conserved global control region for Hox gene regulation in annelids and shows convergent evolution of cluster-wide regulatory mechanisms in vertebrates and spiralians.

This paper introduces a physics-based model explaining how cells maintain histone methylation patterns after division, validated by simulations and experimental data.

Pleiades, a whole-genome epigenetic model, detects Alzheimer's and Parkinson's disease from plasma cell-free DNA with high accuracy.

This study investigates histone-based chromatin regulation in Annelida using multi-omics approaches, revealing lineage-specific effects on histone repertoires and functional implications of histone variants.

The paper analyzes methylomes in annelids to show ancestral epigenetic erosion during development and aging, with gene body methylation linked to transcription and TE silencing.

The paper shows that temporal shifts in trunk formation underpin larval diversification in annelids and bilaterian life cycles through comparative genomic and transcriptomic analysis.

This paper analyzes the genome of Osedax frankpressi to show how genetic changes enable symbiotic digestion of bone, with reduced immunity genes and expanded protease genes.