Kero Guynes

Zygotic genome activation is timed by the egg DNA-to-cytoplasm ratio across animals

The paper investigates ZGA timing across 61 animal species and finds that genome size to cytoplasm volume ratio predicts ZGA onset.

Convergent evolution of cluster-wide Hox gene regulation in Bilateria

The paper identifies a conserved global control region for Hox gene regulation in annelids and shows convergent evolution of cluster-wide regulatory mechanisms in vertebrates and spiralians.

A chromosome-level assembly and functional genomic resources for the model annelid Capitella teleta

The paper presents a chromosome-level genome assembly and functional genomic resources for Capitella teleta, improving upon an outdated reference and enabling better analysis of multi-omic data.

The evolution and developmental dynamics of histone-based chromatin regulation in Annelida

This study investigates histone-based chromatin regulation in Annelida using multi-omics approaches, revealing lineage-specific effects on histone repertoires and functional implications of histone variants.

Annelid methylomes reveal ancestral developmental and ageing-associated epigenetic erosion across Bilateria

The paper analyzes methylomes in annelids to show ancestral epigenetic erosion during development and aging, with gene body methylation linked to transcription and TE silencing.

Annelid functional genomics reveal the origins of bilaterian life cycles

The paper shows that temporal shifts in trunk formation underpin larval diversification in annelids and bilaterian life cycles through comparative genomic and transcriptomic analysis.

Early embryogenesis and organogenesis in the annelid Owenia fusiformis

This study describes the embryonic and larval development of Owenia fusiformis, identifying key developmental stages and highlighting the complexity of its nervous system formation.