Author

Malathi Manuel

Christian Medical College, VelloreORCID 0000-0002-2575-9721Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:ecology & biodiversity· 1 Approach:experimental assay· 1 Assay:metagenomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Adrian J. F. LutyiD· 3 shared Sitara Swarna Rao AjjampuriD· 3 shared David ChaimaiD· 2 shared Judd L. WalsoniD· 2 shared Khumbo KaluaiD· 2 shared M. IbikounléiD· 2 shared Nils PilotteiD· 2 shared Robin L. BaileyiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

Adrian J. F. LutyORCID

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3 papers

Recent·Most cited

Determination of diagnostic cycle threshold (Ct) cut-offs for qPCR-based prevalence surveys of soil-transmitted helminth infections

Malathi Manuel, Nils Pilotte, Joseph W. S. Timothy, Sean R. Galagan, Gideon John Israel, Craig T. Connors, Victor Omballa, Monica Pechanec Voss, Ushashi Chand Dadwal, Andrew M. Gonzalez, Justine Ahlonsou, David Chaima, Zayina Zondervenni Manoharan, Doug Rains, Kristjana Ásbjörnsdóttir, , Sitara Swarna Rao Ajjampur

The paper establishes Ct cut-offs for qPCR to detect transmissible soil-transmitted helminth infections using data from 29,980 samples.

bioRxiv · Jan 5, 2026 · PreprintMicrobiology

Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets

Marina Papaiakovou, Andrea Waeschenbach, Olumide Ajibola, Sitara Swarna Rao Ajjampur, Roy Malcolm Anderson, Robin L. Bailey, Jade Benjamin‐Chung, Maria Cambra-Pellejà, Nicolas R. Caro, David Chaima, Rubén O. Cimino, Piet Cools, Anélsio Cossa, Julia C. Dunn, Sean R. Galagan, , Stephen R. Doyle

The paper assesses genetic diversity of soil-transmitted helminths across regions and evaluates its impact on molecular diagnostic targets using low-coverage genome sequencing and in vitro assays.

Nature Communications · Jul 10, 2025Peer-reviewedGenomics

Environmental surveillance of soil-transmitted helminths and other enteric pathogens in settings without networked wastewater infrastructure

Edoux Joel Siko, Kendra J. Gallo, Zayina Zondervenni Manoharan, Ajith Kumar Muthukumar, Heather K. Amato, Christopher LeBoa, Michael Harris, Venkateshprabhu Janagaraj, Malathi Manuel, Tintu Varghese, Parfait Houngbégnon, Nils Pilotte, Bernadin Bouko, Souad Saïdou, Adrian J. F. Luty, , Amy J. Pickering

The paper evaluates sampling strategies for detecting soil-transmitted helminths and other enteric pathogens in non-networked sanitation settings using wastewater and soil samples.

PLOS Water · Jan 23, 2025Peer-reviewedMicrobiology