Author

Jan T. Czerminski

University of Massachusetts Chan Medical SchoolORCID 0000-0002-2576-4192Unclaimed ORCID profile · follow to get notified of new preprints

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Developmental Biology· 1

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Jeanne Bentley LawrenceiD· 1 shared Oliver D. KingiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperDevelopmental Biology

Jeanne Bentley LawrenceORCID

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1 paper

Recent·Most cited

Modeling Down syndrome neurodevelopment with isogenic cerebral organoids

Jan T. Czerminski, Oliver D. King, Jeanne Bentley Lawrence

This study uses isogenic cerebral organoids to examine transcriptomic and cell-type differences between trisomic and disomic iPSC lines, finding that Trisomy 21 correlates with increased Aβ-40 levels but not other non-chr21 DEGs.

bioRxiv · May 25, 2022 · PreprintDevelopmental Biology