Integrating glycosylation in de novo protein design with ReGlyco Binder Design Filter
The paper integrates glycosylation filtering into a protein design pipeline to improve efficiency and reduce costs in binder design.
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National University of Ireland, MaynoothORCID 0000-0002-2586-2542Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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The paper integrates glycosylation filtering into a protein design pipeline to improve efficiency and reduce costs in binder design.
Silvia D’Andrea, Edward N. Schmidt, Duong T. Bui…·Elisa Fadda
This study investigates Siglec-6's binding mechanism to gangliosides, showing it relies on both conserved and membrane-associated residues for effective recognition.
Marium Khaleque, Beatrice Tropea, Ojas Singh…·Benjamin Luke Schulz
This paper identifies sequence determinants that regulate oligosaccharyltransferase (OST) catalytic efficiency and glycosylation specificity in proteins.