Silvia D’Andrea

The paper shows that O-glycans in LRP1's ligand-binding domains differentially modulate uptake of tau and amyloid beta, but not RAP or ApoE.

This study investigates Siglec-6's binding mechanism to gangliosides, showing it relies on both conserved and membrane-associated residues for effective recognition.

This study identifies key residues in Siglec-10 involved in ligand recognition and shows that antibody blockade can restore CAR-T cell cytotoxicity.

This paper characterizes the glycosylation of soluble CD52 and identifies its role in immune suppression through interactions with HMGB1 and SIGLEC-10.

The paper introduces GlycoShape, an open-access database and tool to restore glycosylation to protein structures using molecular dynamics simulations and public structural data.

The paper identifies mutations in candidate genes for parauberculosis resistance in sheep using genome-wide scans and direct sequencing.