Interspecies differences in proteome turnover kinetics are correlated with lifespans and energetic demands
Kyle Swovick, Denis Firsanov, Kevin A. Welle, Jennifer R. Hryhorenko, John Pierce Wise, Craig George, Todd L. Sformo, Andrei Seluanov, Vera A. Gorbunova, Sina Ghaemmaghami
The paper measures protein turnover rates in fibroblasts from long-lived species and finds slower turnover correlates with longer lifespan and reduced ROS.
Molecular & Cellular Proteomics · Dec 28, 2020Peer-reviewedSystems Biology