Author
University of RochesterORCID 0000-0003-1573-0113Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Seyed Ali Biashad, Eric C. Hillpot, Francesco Morandini…·Vera A. Gorbunova
This study shows that fucoidan, a seaweed-derived polysaccharide, extends healthspan and lifespan in aged mice by activating SIRT6, which reduces LINE1 retrotransposon activity and epigenetic aging.
Matthew A. Simon, Jiping Yang, Jonathan Gigas…·Vera A. Gorbunova
The paper identifies a SIRT6 variant enriched in centenarians that improves genome stability through enhanced mADPr activity and interaction with Lamin A.
Kyle Swovick, Denis Firsanov, Kevin A. Welle…·Sina Ghaemmaghami
The paper measures protein turnover rates in fibroblasts from long-lived species and finds slower turnover correlates with longer lifespan and reduced ROS.