Shamaine Wei Ting Ho

Gene-Family Encoding Boosts Domain-Adapted Single-Cell Language Models

This paper introduces gene-family encoding to improve domain-adapted single-cell language models, showing better performance in embedding-based and generative tasks on gastric-cancer data.

Single-cell Pharmacogenomic Landscapes of Epigenetic Drug Resistance Revealed by Gastric Cancer Perturb-seq

This study uses Perturb-seq to analyze pharmacogenomic interactions in gastric cancer, revealing gene-drug relationships and resistance mechanisms.

Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution

This study integrates spatial transcriptomics and single-cell data from gastric cancer samples to reveal tumor ecosystem dynamics, evolutionary trajectories, and immune microenvironment features.