Jimmy Bok Yan So

TIM3+ Tumor Associated M2 Macrophages Impair Antitumor T Cell Immunity and Promote Gastric Cancer Progression and Peritoneal Metastasis

This study shows TIM3 on M2 macrophages promotes gastric cancer progression and metastasis by suppressing T cell immunity, and TIM3 blockade combined with immunotherapy and chemotherapy improves outcomes.

Single-cell Pharmacogenomic Landscapes of Epigenetic Drug Resistance Revealed by Gastric Cancer Perturb-seq

This study uses Perturb-seq to analyze pharmacogenomic interactions in gastric cancer, revealing gene-drug relationships and resistance mechanisms.

Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution

This study integrates spatial transcriptomics and single-cell data from gastric cancer samples to reveal tumor ecosystem dynamics, evolutionary trajectories, and immune microenvironment features.

Spatially resolved niche and tumor microenvironmental alterations in gastric cancer peritoneal metastases

This study identifies transcriptomic and immune features of gastric cancer peritoneal metastases, highlighting predictive markers and therapeutic targets in the tumor microenvironment.