GenomicsbioRxivPreprint
Connecting polygenic disease risk to cell states and regulatory programs through single-cell chromatin accessibility
Liyang Yu, Luke T. Deary, Qiaoxue Liu…·Siming Zhao
SCADS integrates GWAS data with scATAC-seq to identify disease-relevant cell states and regulatory programs, showing heterogeneity in immune cell types for inflammatory bowel disease.
DOI 10.64898/2026.04.27.721080