Loss of NMDA receptor function during development results in decreased KCC2 expression and increased neurons in the zebrafish forebrain.
Amalia J. Napoli, Stephanie Laderwager, Josiah D. Zoodsma, Bismi Biju, Olgerta Mucollari, Sarah K. Schubel, Christieann Aprea, Aaliya Sayed, Kiele Morgan, Annelysia Napoli, Stephanie Flanagan, Lonnie P. Wollmuth, Howard I. Sirotkin
This study shows that loss of NMDA receptor function in zebrafish leads to reduced KCC2 expression and increased neurons in the forebrain during post-embryonic neurogenesis.
Scientific Reports · Feb 9, 2024Peer-reviewedNeuroscience