Harold A. Burgess

This study shows that elevated temperature worsens arrhythmia and seizures in a zebrafish model of Timothy syndrome, suggesting fever may increase risk for TS patients.

The paper develops a method to ablate specific synaptic connections in neurons using optogenetic tools, demonstrating its application in zebrafish to disrupt functional connectivity and observe behavioral effects.

The paper shows that parp1 deletion rescues cerebellar hypotrophy in xrcc1 mutant zebrafish, suggesting PARP1 inhibition could be therapeutic for neurological disorders.

This study examines the role of srrm4 in zebrafish neural development and finds minimal phenotypic effects from mutations.

This study identifies a cerebellar-prepontine circuit that mediates tonic immobility in larval zebrafish in response to inescapable threats.

This study develops a zebrafish model with CRISPR-mediated NMDAR gene lesions to investigate NMDAR function in early nervous system development and behavior.

This study identifies a cluster of posterior tuberculum neurons in zebrafish larvae that mediate intrinsic motor asymmetry through Notch signaling.

The paper identifies a cluster of prepontine neurons in zebrafish that drive flexible escape behaviors in response to less urgent threats, distinct from the fast escape pathway.

The paper generates and annotates new Cre transgenic zebrafish lines for intersectional genetic experiments and integrates them with a brain atlas for spatial search.

This study aligns two zebrafish brain atlases using symmetric diffeomorphic normalization, improving registration precision and preserving morphology.