NeurosciencebioRxivPreprint
MEG3 Enhances Survival of Developing Human Neurons with CLCN4-Linked Autophagy Impairment
Dayeon Kim, Yongjun Koh, Hyeon Seong Jeong…·Jinju Han
The paper identifies CLCN4 variants causing neuronal cell death and autophagy impairment, showing MEG3 restoration rescues these defects in human neurons.
DOI 10.1101/2025.07.16.665078