Lipika Baidya

This study develops a coarse-grained model of PAR and uses molecular dynamics to show PAR undergoes stronger structural transitions than RNA in response to divalent ions due to preferential ion binding and bridging.

This study shows how Co2+ binding drives folding of the NiCo riboswitch by stabilizing non-canonical base pairs and modulating conformational flexibility at helical junctions.

This study investigates how Mg2+ and Ca2+ ions influence the folding of a tetraloop RNA motif through direct and indirect binding modes, revealing non-native metal-RNA contacts and their impact on folding stability.