Author

Wiktor Prus

Institute of Fundamental Technological ResearchORCID 0000-0002-2665-5545Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Systems Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Tomasz Lipniacki BiD· 3 shared Frederic GrabowskiiD· 2 shared Maciej CzerkiesiD· 2 shared Marek KochańczykiD· 2 shared Zbigniew KorwekiD· 2 shared Ilona KosiukiD· 1 shared Joanna Jaruszewicz-BłońskaiD· 1 shared Nazanin AmirinejadiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersSystems Biology

Tomasz Lipniacki BORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Type III interferons may suppress viral infections by triggering cell death

Wiktor Prus, Frederic Grabowski, Paulina Koza, Zbigniew Korwek, Maciej Czerkies, Paulina Kaczyńska, Nazanin Amirinejad, Marek Kochańczyk, Tomasz Lipniacki B

This study shows that type III interferons suppress viral infections by promoting rapid cell death in infected epithelial cells, unlike type I interferons which mainly induce ISG expression.

bioRxiv · Sep 9, 2024 · PreprintImmunology

Antagonism between viral infection and innate immunity at the single-cell level

Frederic Grabowski, Marek Kochańczyk, Zbigniew Korwek, Maciej Czerkies, Wiktor Prus, Tomasz Lipniacki

The paper models the antagonism between viral infection and innate immunity at the single-cell level using an agent-based stochastic approach, revealing three levels of viral interference with the immune response.

PLoS Pathogens · Sep 5, 2023Peer-reviewedSystems Biology

A plausible identifiable model of the canonicalNF-kB signaling pathway

Joanna Jaruszewicz-Błońska, Ilona Kosiuk, Wiktor Prus, Tomasz Lipniacki

The paper reduces a complex NF-kB pathway model to a simpler identifiable model that retains key dynamics and can be used for further studies.

bioRxiv · Jun 9, 2022 · PreprintSystems Biology