Author

Jacob Canepa

The University of Texas Southwestern Medical CenterORCID 0000-0002-2719-172XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:cryo-EM· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Binh An NguyeniD· 2 shared Lorena SaelicesiD· 2 shared Preeti SinghiD· 2 shared Shumaila AfriniD· 2 shared Virender Pratap SinghiD· 2 shared Yasmin AhmediD· 2 shared Aleksandra WosztyliD· 1 shared Andrew S. LemoffiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiophysics

Binh An NguyenORCID

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2 papers

Recent·Most cited

BiophysicsCommunications BiologyPeer-reviewedJul 27, 2024

Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis

Binh An Nguyen, Virender Pratap Singh, Shumaila Afrin…·Lorena Saelices

The paper uses cryo-EM to show that cardiac ATTRwt amyloid fibrils from four patients are structurally identical, supporting their consistent clinical presentation.

26 citationstop 1%

humancryo-EM

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Molecular BiologybioRxivPreprintMay 14, 2024

Multi-organ structural homogeneity of amyloid fibrils in ATTRv-T60A amyloidosis patients, revealed by Cryo-EM

María del Carmen Fernández‐Ramírez, Binh An Nguyen, Preeti Singh…·Lorena Saelices

The paper uses cryo-EM to show that ATTR-T60A amyloid fibrils from multiple organs in patients have a consistent structural conformation.

7 citations

humanexperimental assay

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