Author

Wojciech Siwek

Harvard UniversityORCID 0000-0002-2720-5191Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

Artur PirógiD· 1 shared Elżbieta ChruścieliD· 1 shared Izma Abdul‐ZaniiD· 1 shared João F. MataiD· 1 shared Justyna TopaiD· 1 shared Lars E.T. JanseniD· 1 shared Mateusz ModzelewskiiD· 1 shared Paweł MikulskiiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Artur PirógORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 21, 2026

STAT3 dual role in sex-biased and differentiation-gated interferon gamma memory

Justyna Topa, Wojciech Snoch, Mateusz Modzelewski…·Wojciech Siwek

The paper investigates the role of STAT3 in IFN-gamma memory in human macrophages, revealing its dual function in repression and recall, and identifies sex-biased and differentiation-dependent mechanisms.

DOI 10.64898/2026.10.21.760183

humanbulk RNA-seq

Molecular BiologyThe EMBO JournalPeer-reviewedJun 5, 2023

STAT1 is required to establish but not maintain IFNγ-induced transcriptional memory

Sahar Tehrani, Paweł Mikulski, Izma Abdul‐Zani…·Lars E.T. Jansen

The paper shows STAT1 is essential for establishing IFNγ-induced transcriptional memory but not for maintaining it, with GBP genes being poised for rapid activation upon secondary exposure.

47 citationstop 3%

humanbulk RNA-seq