Artur Piróg

The paper investigates the role of STAT3 in IFN-gamma memory in human macrophages, revealing its dual function in repression and recall, and identifies sex-biased and differentiation-dependent mechanisms.

This paper introduces a novel serum peptidomics workflow that improves peptide yield, throughput, and recovery, identifying subtype-specific peptide biomarkers for stroke subtypes.

The paper benchmarks five proteomics workflows for sEV analysis, showing Exo-insert and Exo-SP3 can identify ~1100 proteins from low-input samples, with performance varying by sEV source.

This study shows that mature tumoroids, grown in 3D culture for ≥10 days, better reflect clinical drug responses in PDAC compared to short-term cultures by capturing microenvironmental effects and transporter-mediated resistance.

The paper describes methods for isolating and analyzing short intracellular polypeptides and small proteins, along with computational tools for data analysis.