Prachi Shah

A gαq signaling pathway in dopaminergic neurons suppresses memory

This study identifies Gq signaling in dopaminergic neurons as a memory suppressor in Drosophila using aversive conditioning and imaging techniques.

Modeling Post-traumatic memory deficits: Repeated head injury effects on Novelty detection in Drosophila

This study shows that repeated head injuries in Drosophila cause dose-dependent behavioral, cellular, and circuit dysfunctions similar to mammalian TBI, highlighting both vulnerability and resilience in the mushroom body circuit.

Anesthesia-triggered dopaminergic bursts actively induce forgetting: a paradigm shift in understanding cold-shock amnesia

This paper shows that anesthesia triggers dopamine release from specific neurons, which actively causes forgetting, challenging the idea that memory loss is passive.

Slit regulates subcellular-specific targeting of dendrites and axons in the Drosophila brain

This study shows that Slit-mediated repulsion between dendrites and axons in Drosophila mushroom body neurons regulates subcellular-specific targeting and affects learning and memory.

Olfactory sensory preconditioning in Drosophila: role of memory forgetting in gating S1/S2 associations

The paper demonstrates olfactory sensory preconditioning in Drosophila, showing that non-paired odors can be associated through memory forgetting mechanisms, with Rac1 inhibition extending the sensory buffer.