The toll-like receptor signalling pathway is altered in iPSC-derived cortical networks from people with bipolar disorder.
Bruna Panizzutti, Chiara C. Bortolasci, Megan K. Ellis, Briana Spolding, Courtney Swinton, Trang T. T. Truong, Cassie Field, Zoe Shih-Jung Liu, Damián Hernández, Greg Roebuck, Ajeet Singh, Bruno Agustini, Robson Zazula, Ana C. Andreazza, Dana El Soufi El Sabbagh, , Ken R. Walder
The paper identifies altered toll-like receptor signalling in iPSC-derived cortical networks from bipolar disorder patients using transcriptome sequencing and differential expression analysis.
Bipolar Disorders · Aug 1, 2026Peer-reviewedNeuroscience