Engineered CRISPR-Cas9 system enables noiseless, fine-tuned and multiplexed repression of bacterial genes
A. Vigouroux, Enno Rainer Oldewurtel, Lun Cui, Sven van Teeffelen, David Bikard
This paper introduces an engineered CRISPR-Cas9 system that enables precise, tunable, and multiplexed repression of bacterial genes by controlling guide RNA complementarity.
Molecular Systems Biology · Mar 1, 2018Peer-reviewedSynthetic Biology