Author

Lun Cui

Institut PasteurORCID 0000-0001-5907-0538Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Organism:bacteria (other)· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

David BikardiD· 2 shared A. VigourouxiD· 1 shared Belen Gutierrez· 1 shared Christophe BécaviniD· 1 shared Enno Rainer OldewurteliD· 1 shared Jérôme Wong-NgiD· 1 shared Sven van TeeffeleniD· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 12 mutual co-author links

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2 shared papersSynthetic Biology

David BikardORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintApr 30, 2018

Genome-wide CRISPR-Cas9 screen in E. coli identifies design rules for efficient targeting

Belen Gutierrez, Jérôme Wong-Ng, Lun Cui…·David Bikard

The paper identifies sequence determinants of CRISPR-Cas9 efficiency in E. coli through a genome-wide screen and develops a sequence-based model to predict cleavage efficiency.

7 citations

E. coliCRISPR screen

𝕏 PostBluesky

Synthetic BiologyMolecular Systems BiologyPeer-reviewedMar 1, 2018

Engineered CRISPR-Cas9 system enables noiseless, fine-tuned and multiplexed repression of bacterial genes

A. Vigouroux, Enno Rainer Oldewurtel, Lun Cui…·David Bikard

This paper introduces an engineered CRISPR-Cas9 system that enables precise, tunable, and multiplexed repression of bacterial genes by controlling guide RNA complementarity.

115 citationstop 3%

bacteria (other)CRISPR screen

𝕏 PostBluesky