Sandra S. Zinkel

TET2 loss impairs MPLA-induced innate immune memory during infection and disrupts hematopoiesis via RIPK1 in mice

This study shows TET2 loss impairs innate immune memory and infection responses in mice, with MPLA pretreatment partially improving these effects and promoting myeloid-biased hematopoiesis.

The broad impact of cell death genes on the human disease phenome

The paper investigates the relationship between cell death gene expression and human phenotypes using GTEx and UK Biobank data, finding significant associations and tissue-specific effects.

Mechanistic Deep Learning Framework on Cell Traits Derived from Single-Cell Mass Cytometry Data

This paper develops a machine learning framework for analyzing mass cytometry data to uncover genetic perturbations and cell-type dynamics in hematopoietic systems.

The genetic architecture of human infectious diseases and pathogen-induced cellular phenotypes

The paper identifies 70 gene-level associations with 26 infectious disease traits using transcriptome-wide association studies and explores their molecular basis and implications for host-pathogen interactions.