TET2 loss impairs MPLA-induced innate immune memory during infection and disrupts hematopoiesis via RIPK1 in mice
Alyssa Jarabek, Xenia D. Davis, Mary Oliver, Yongchao Wang, Heidi Chen, Julia K. Bohannon, Sandra S. Zinkel
This study shows TET2 loss impairs innate immune memory and infection responses in mice, with MPLA pretreatment partially improving these effects and promoting myeloid-biased hematopoiesis.
bioRxiv · Sep 8, 2025 · PreprintCancer Biology