NeuroscienceNature NeurosciencePeer-reviewed
TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy
Baiping Wang, Heidi Martini‐Stoica, Chuangye Qi…·Hui Zheng
This study shows that TFEB-v-ATPase signaling regulates lysosomal function and microglial activation in tauopathy by impairing lysosomal acidification and altering microglia responses.