NeuroscienceFrontiers in Behavioral NeurosciencePeer-reviewed
Constitutive activity of the inhibitory G protein pathway mediated by non-visual opsin Opn7b reduces cFos activity in stress and fear circuits and modulates avoidance behavior
Hanna Böke, Hannah Schulte, Maria Worm…·Katharina Spoida
This study shows that Opn7b, a constitutively active GPCR, reduces cFos expression and modulates avoidance behavior in mice by activating the Gi/o pathway in specific brain regions.
DOI 10.3389/fnbeh.2025.1540947