Author

Brix Mücher

Ruhr University BochumORCID 0009-0002-7233-8679Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Ida SivekeiD· 2 shared Stefan HerlitzeiD· 2 shared Aida Garrido‐CharlesiD· 1 shared Deniz DalkaraiD· 1 shared Hanna BökeiD· 1 shared Hannah Schulte· 1 shared Julia Bihorac· 1 shared Katharina SpoidaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Ida SivekeORCID

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2 papers

Recent·Most cited

Constitutive activity of the inhibitory G protein pathway mediated by non-visual opsin Opn7b reduces cFos activity in stress and fear circuits and modulates avoidance behavior

Hanna Böke, Hannah Schulte, Maria Worm, Julia Bihorac, Brix Mücher, Martin Hadamitzky, Ida Siveke, Stefan Herlitze, Katharina Spoida

This study shows that Opn7b, a constitutively active GPCR, reduces cFos expression and modulates avoidance behavior in mice by activating the Gi/o pathway in specific brain regions.

Frontiers in Behavioral Neuroscience · Jun 5, 2025Peer-reviewedNeuroscience

Guiding G protein signaling by target enhancement of GPCRs

Brix Mücher, Aida Garrido‐Charles, Lukas Cyganek, Tobias Bruegmann, Deniz Dalkara, Ida Siveke, Stefan Herlitze

The paper introduces tools to selectively enhance Gi/o-mediated GIRK currents in excitable cells using light-activated GPCRs.

bioRxiv · Feb 6, 2025 · PreprintNeuroscience