Robert P. L. Wisse

Quantification of double stranded DNA breaks and telomere length as proxies for corneal damage and replicative stress in 64 human keratoconus corneasThe role of DNA damage in the development of keratoconus

This study quantifies DNA damage and telomere length in keratoconus corneas to assess oxidative stress and replicative stress, finding no significant DNA damage differences but longer telomeres in keratoconus.

mTOR complex 1 pathway activation in severe keratoconus; the functional implications of GWAS identified loci.

The paper identifies up-regulation of the mTORC1 pathway in keratoconus corneas and confirms differential expression of GWAS risk loci.