Author

Ruizhen Yang

Hong Kong Baptist UniversityORCID 0000-0002-2845-0762Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Bo Yuan HuangiD· 1 shared Feng LiuiD· 1 shared Jue ShiiD· 1 shared Yang LiiD· 1 shared Yanting ZhuiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperSystems Biology

Bo Yuan HuangORCID

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1 paper

Recent·Most cited

Variable sensitivity to DNA damaging chemotherapeutic modulated by cell type-dependent bimodal p53 dynamics

Ruizhen Yang, Bo Yuan Huang, Yanting Zhu, Yang Li, Feng Liu, Jue Shi

This study identifies bimodal p53 dynamics as a mechanism modulating resistance to DNA damaging chemotherapy, showing that ATM expression determines sensitivity and that inhibiting Mdm2 and Wip1 can sensitize resistant cells.

Science Advances · Dec 7, 2018Peer-reviewedSystems Biology