Author

Yanting Zhu

Hong Kong Baptist UniversityORCID 0009-0006-1854-4809Unclaimed ORCID profile · follow to get notified of new preprints

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Yanting Zhu1 paper · ShanghaiTech University

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Jue ShiiD· 2 shared Bo Yuan HuangiD· 1 shared Feng LiuiD· 1 shared Jun XieiD· 1 shared Lichun ZhangiD· 1 shared Ruizhen YangiD· 1 shared Xiao LiangiD· 1 shared Yang LiiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersSystems Biology

Jue ShiORCID

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2 papers

Recent·Most cited

Systems BiologyBMC BiologyPeer-reviewedApr 11, 2022

Single-cell transitional dynamics unravel stimulus- and cell type-dependent signaling outputs of distinct p53 regulatory feedback motifs

Jun Xie, Lichun Zhang, Yanting Zhu…·Jue Shi

The paper uses single-cell imaging and mathematical modeling to analyze p53 pathway dynamics in response to chemotherapeutics, identifying novel feedback motifs and their role in context-specific signaling responses.

5 citations

humanspatial transcriptomics

𝕏 PostBluesky

Systems BiologyScience AdvancesPeer-reviewedDec 7, 2018

Variable sensitivity to DNA damaging chemotherapeutic modulated by cell type-dependent bimodal p53 dynamics

Ruizhen Yang, Bo Yuan Huang, Yanting Zhu…·Jue Shi

This study identifies bimodal p53 dynamics as a mechanism modulating resistance to DNA damaging chemotherapy, showing that ATM expression determines sensitivity and that inhibiting Mdm2 and Wip1 can sensitize resistant cells.

46 citations

humanproteomics

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