An essential role for miR-15/16 in Treg suppression and restriction of proliferation
Kristina Johansson, John D Gagnon, Simon K. Zhou, Marlys S. Fassett, Andrew Schroeder, Robin Kageyama, Rodriel A. Bautista, Hewlett Pham, Prescott G. Woodruff, Karl Mark Ansel
This study shows that miR-15/16 in Tregs is essential for immune tolerance by restricting proliferation and maintaining suppressive function, preventing inflammation.
Cell Reports · Oct 1, 2023Peer-reviewedMolecular Biology