Therapeutic effects of a purified chitin-binding protein from Moringa oleifera seeds on irinotecan-induced intestinal mucositis in mice
Kayanny Queiroz Ferreira, Luana David do Carmo, Liviane Maria Alves Rabelo, Tiago Deiveson Pereira Lopes, Deysi Viviana Tenazoa Wong, Aurilene Gomes Cajado, Renata Ferreira de Carvalho Leitão, Daniele O. B. Sousa, Nylane Maria Nunes de Alencar
This study evaluates the protective effect of Mo-CBP4 against irinotecan-induced intestinal mucositis in mice, showing reduced inflammation, oxidative stress, and improved survival without affecting chemotherapy efficacy.
bioRxiv · Nov 27, 2024 · PreprintPharmacology & Toxicology