Julia Marchetti

The paper identifies 219 human tandem repeat proteins that bind RNA using sequence and structural methods, showing their combined effectiveness over individual approaches.

This study evaluates AlphaFold2's ability to predict ensemble protein conformations and finds it struggles with conformational diversity, with performance worsening as diversity increases.

The paper shows that evolutionary rates of intrinsically disordered proteins correlate with conformational diversity, suggesting that structural constraints from selected conformers influence rate heterogeneity.

The paper compares structural constraints in ordered and disordered protein ensembles, finding similar proportions of constrained sites and long-range contacts.